Drug-DNA complexation as the key factor in photosensitized thymine dimerization.
نویسندگان
چکیده
The crucial role of photosensitizer@DNA complexation in the formation of cyclobutane pyrimidine dimers (CPDs) has been demonstrated using femtosecond and nanosecond transient absorption and emission measurements in combination with in vitro DNA damage assays. This finding opens the door to re-evaluate the mechanisms involved in CPDs photosensitized by other chemicals.
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ورودعنوان ژورنال:
- Physical chemistry chemical physics : PCCP
دوره 19 7 شماره
صفحات -
تاریخ انتشار 2017